Chul Sik Kim Selected Research

herbimycin

10/2015	17-Allylamino-17-demethoxygeldanamycin and Herbimycin A Induce Cell Death by Modulating β-Catenin and PI3K/AKT Signaling in FRO Anaplastic Thyroid Carcinoma Cells.
12/2014	Herbimycin A inhibits cell growth with reversal of epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells.

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Chul Sik Kim Research Topics

Disease

12	Anaplastic Thyroid Carcinoma 05/2017 - 04/2013
9	Type 2 Diabetes Mellitus (MODY) 01/2020 - 08/2005
9	Insulin Resistance 03/2017 - 06/2004
7	Thyroid Neoplasms (Thyroid Cancer) 01/2019 - 12/2005
3	Atherosclerosis 11/2016 - 12/2006
3	Cardiovascular Diseases (Cardiovascular Disease) 11/2016 - 07/2009
3	Diabetic Nephropathies (Diabetic Nephropathy) 11/2015 - 05/2009
3	Abdominal Obesity 06/2011 - 06/2004
2	Diabetes Mellitus 01/2021 - 03/2016
2	Chronic Kidney Failure (Chronic Renal Failure) 08/2016 - 06/2014
2	Prediabetic State (Prediabetes) 04/2016 - 10/2013
2	Proteinuria 01/2015 - 05/2009
2	Albuminuria 01/2015 - 04/2014
1	Body Weight (Weight, Body) 01/2021
1	Obesity 01/2021
1	Weight Loss (Weight Reduction) 01/2021
1	Carotid Artery Diseases 01/2020
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2018
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 02/2017
1	Lymphoma (Lymphomas) 02/2017
1	Graves Disease (Basedow Disease) 01/2017
1	Graves Ophthalmopathy 01/2017
1	Thyroid Diseases (Thyroid Disease) 01/2017
1	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2015

Drug/Important Bio-Agent (IBA)

7	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 06/2004
7	Proteins (Proteins, Gene)FDA Link 01/2019 - 05/2009
7	Heat-Shock Proteins (Heat-Shock Protein)IBA 10/2017 - 09/2014
6	Insulin (Novolin)FDA Link 03/2017 - 02/2006
5	Triglycerides (Triacylglycerol)IBA 03/2017 - 12/2006
5	LipidsIBA 12/2013 - 06/2004
4	SurvivinIBA 06/2018 - 02/2015
4	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2018 - 08/2016
3	Histone Deacetylase InhibitorsIBA 01/2019 - 02/2015
3	HDL CholesterolIBA 03/2017 - 12/2006
3	LDL Lipoproteins (beta Lipoproteins)IBA 12/2013 - 12/2006
3	CholesterolIBA 12/2013 - 07/2009
3	oxidized low density lipoproteinIBA 12/2013 - 12/2006
3	LDL CholesterolIBA 06/2011 - 12/2006
2	evodiamineIBA 01/2019 - 11/2018
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2019 - 02/2016
2	LC15-0444IBA 01/2018 - 10/2017
2	5- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA 10/2017 - 02/2015
2	Proto-Oncogene Proteins c-bcl-2 (Proto Oncogene Proteins c bcl 2)IBA 10/2017 - 05/2017
2	Mitogen-Activated Protein Kinase 3IBA 10/2017 - 02/2017
2	Paclitaxel (Taxol)FDA LinkGeneric 05/2017 - 04/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2017 - 02/2017
2	Mitogen-Activated Protein KinasesIBA 05/2017 - 05/2009
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 04/2016 - 01/2015
2	belinostatIBA 02/2016 - 02/2015
2	ApigeninIBA 12/2015 - 04/2013
2	herbimycinIBA 10/2015 - 12/2014
2	tanespimycin (17AAG)IBA 10/2015 - 04/2015
2	CreatinineIBA 01/2015 - 04/2014
2	Thioctic Acid (Lipoic Acid)IBA 05/2009 - 01/2009
2	AntioxidantsIBA 05/2009 - 01/2009
1	Liraglutide FDA Link 01/2021
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 06/2018
1	Metformin (Glucophage)FDA LinkGeneric 01/2018
1	Luteinizing Hormone (Lutropin)FDA LinkGeneric 01/2018
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2018
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2018
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2018
1	Protein Kinases (Protein Kinase)IBA 10/2017
1	Adenosine Monophosphate (AMP)IBA 10/2017
1	Death Domain ReceptorsIBA 05/2017
1	celastrolIBA 05/2017
1	C-Reactive ProteinIBA 03/2017
1	Janus Kinase 2IBA 02/2017
1	cucurbitacin BIBA 02/2017
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 02/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2017
1	Immunoglobulin G (IgG)IBA 01/2017
1	Immunoglobulins (Immunoglobulin)IBA 01/2017
1	cupric sulfide (CuS)IBA 11/2016
1	Glucagon-Like Peptide-1 ReceptorIBA 11/2016
1	IncretinsIBA 11/2016
1	Hypoglycemic Agents (Hypoglycemics)IBA 11/2016
1	Hormones (Hormone)IBA 11/2016
1	Glucagon-Like Peptides (Enteroglucagon)IBA 11/2016
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 10/2016
1	triptolideIBA 10/2016
1	6- chloro- 9- (4- methoxy- 3,5- dimethylpyridin- 2- ylmethyl)- 9H- purin- 2- ylamineIBA 10/2016
1	VildagliptinIBA 08/2016
1	Sitagliptin Phosphate (Januvia)FDA Link 08/2016
1	LinagliptinIBA 08/2016
1	theasinensin AIBA 02/2016
1	Vorinostat FDA Link 02/2016
1	trichostatin A (A 300)IBA 02/2016
1	TNF-Related Apoptosis-Inducing LigandIBA 12/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2015
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2015
1	CateninsIBA 10/2015
1	Inhibitor of Apoptosis ProteinsIBA 02/2015
1	X-Linked Inhibitor of Apoptosis ProteinIBA 02/2015
1	Angiotensin Receptor AntagonistsIBA 01/2015
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2015
1	Pentoxifylline (Trental)FDA LinkGeneric 01/2015

Therapy/Procedure

2	Glycemic Control 01/2019 - 01/2015
2	Therapeutics 11/2016 - 01/2015